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Features of Extra Super Tadarise One of the causes of premature ejaculation is a lack of serotonin, which leads to excessive secretion of adrenaline, which causes excessive stress on the sympathetic nervous system and a state of excitement and tension. This causes ejaculation at an unintended time. Serotonin, a transmitter in the brain, is said to work to balance feelings of excitement and anxiety by suppressing dopamine, which is highly effective in increasing pleasure, and noradrenaline, which responds to tension and stress. .